Medical Adhesives Mechanical Testing Solutions

Medical adhesives are specialized substances used to bond medical devices, tissues, or other components together. They must comply with strict biocompatibility requirements and are vital in surgeries, wound care, and medical equipment manufacturing. Adhesives used in medical applications require mechanical testing to ensure their strength, durability, and compatibility with various substrates. Sutures are often classified as medical adhesives because they function to mechanically close and secure tissue interfaces, similar to how adhesives bond surfaces together.

ADMET testing systems are trusted by leading medical device manufacturers, universities, and research laboratories to determine the mechanical properties and endurance limits of biomaterials, medical devices and implants. Our systems meet FDA 21 CFR part 11 requirements and are capable of performing tension, compression, flexural, adhesive, torsion, axial-torsion and planar biaxial tests according to ASTM and ISO standards. Our ability to design a system to fit specific needs allows ADMET to provide testing solutions for even the most unique and demanding applications.

Types of Medical Adhesives

Tissue adhesive for the topical approximation of skin

A tissue adhesive for the topical approximation of skin is a device intended for topical closure of surgical incisions, including laparoscopic incisions, and simple traumatic lacerations that have easily approximated skin edges. Tissue adhesives for the topical approximation of skin are Class II medical devices and may be used in conjunction with, but not in place of, deep dermal stitches.

Tissue adhesive for non-topical use

A tissue adhesive for non-topical use is a Class III medical device that is used for adhesion of internal tissues and vessels. Examples of use include the embolization of brain arteriovenous malformation and ophthalmic surgery,

Tissue adhesive with adjunct wound closure device intended for the topical approximation of skin

A tissue adhesive with adjunct wound closure is a Class II medical device intended for topical application only to hold closed easily approximated skin edges of wounds from surgical incisions, including punctures from minimally invasive surgery, and simple, thoroughly cleansed, trauma-induced lacerations.

Types of adhesives include:

  1. Cyanoacrylate Adhesives: Quick-setting and used for minor wound closures.
  2. Silicone-Based Adhesives: Known for flexibility and biocompatibility, often used in skin attachments and prosthetics.
  3. Epoxy Resins: Offer high mechanical and thermal resistance; used in bonding medical devices.
  4. Acrylic Adhesives: Provide high tensile and shear strength; adhere well to various materials.
  5. Pressure-Sensitive Adhesives (PSAs): Used in medical tapes and patches; adhere with applied pressure.
  6. Polyurethane Adhesives: Versatile with excellent wear resistance; often used in flexible medical devices.
  7. Fibrin Sealants: Derived from blood components and used for hemostasis during surgical procedures.
  8. Hydrogel Adhesives: Water-based and gentle on the skin; commonly used in wound care and ECG electrodes.

Sutures

Sutures often considered the baseline for wound closure techniques, play a crucial role in the medical field. When it comes to developing new medical adhesives, sutures serve as a comparative standard for evaluating the efficacy and mechanical properties of adhesive products. This assessment includes tensile, shear, and peel tests to ensure that medical adhesives can meet or exceed the performance characteristics of traditional suturing methods. By understanding the mechanical benchmarks set by sutures, developers, and manufacturers can optimize adhesive technologies for various medical applications.

Common Medical Adhesive Test Types & Standards:

Peel testing at cryogenic temperatures

Peel Testing is a mechanical testing procedure used to measure the adhesive strength of materials by assessing the force required to separate two bonded surfaces. Some peel testing standards of medical adhesives include: